(PharmaNewsWire.Com, September 29, 2017 ) According to the recently published report 'Steroid Hormone Receptor ERR1-Pipeline Review, H2 2017'; Steroid Hormone Receptor ERR1 (Estrogen Receptor Like 1 or Estrogen Related Receptor Alpha or Nuclear Receptor Subfamily 3 Group B Member 1 or NR3B1 or ESRRA) pipeline Target constitutes close to 5 molecules. Out of which approximately 3 molecules are developed by companies and remaining by the universities/institutes.
Steroid Hormone Receptor ERR1 (Estrogen Receptor Like 1 or Estrogen Related Receptor Alpha or Nuclear Receptor Subfamily 3 Group B Member 1 or NR3B1 or ESRRA)-Estrogen-related receptor alpha (ERRα) or Steroid hormone receptor ERR1 is a nuclear receptor that is encoded by the estrogen related receptor alpha (ESRRA) gene. ERRα regulates genes involved in mitochondrial biogenesis, gluconeogenesis, and fatty acid metabolism. ERRα acts as a transcriptional activator of CYP11B1 and CYP11B2 which indicates that this nuclear receptor may be required for the production of cortisol and aldosterone in the adrenal gland.
The report 'Steroid Hormone Receptor ERR1-Pipeline Review, H2 2017' outlays comprehensive information on the Steroid Hormone Receptor ERR1 (Estrogen Receptor Like 1 or Estrogen Related Receptor Alpha or Nuclear Receptor Subfamily 3 Group B Member 1 or NR3B1 or ESRRA) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type; that are being developed by Companies / Universities.
It also reviews key players involved in Steroid Hormone Receptor ERR1 (Estrogen Receptor Like 1 or Estrogen Related Receptor Alpha or Nuclear Receptor Subfamily 3 Group B Member 1 or NR3B1 or ESRRA) targeted therapeutics development with respective active and dormant or discontinued projects. Currently, The molecules developed by companies in Preclinical and Discovery stages are 2 and 1 respectively. Similarly, the universities portfolio in Preclinical stages comprises 2 molecules, respectively. Report covers products from therapy areas Metabolic Disorders and Oncology which include indications Breast Cancer, Obesity, Type 2 Diabetes and Multiple Myeloma (Kahler Disease).
List of Tables Number of Products under Development by Stage of Development, H2 2017 Number of Products under Development by Therapy Areas, H2 2017 Number of Products under Development by Indication, H2 2017 Number of Products under Development by Companies, H2 2017 Products under Development by Companies, H2 2017 Number of Products under Investigation by Universities/Institutes, H2 2017 Products under Investigation by Universities/Institutes, H2 2017 Number of Products by Stage and Mechanism of Actions, H2 2017 Number of Products by Stage and Route of Administration, H2 2017 Number of Products by Stage and Molecule Type, H2 2017 Pipeline by Lead Pharma Holding BV, H2 2017 Dormant Projects, H2 2017
List of Figures Number of Products under Development by Stage of Development, H2 2017 Number of Products under Development by Therapy Areas, H2 2017 Number of Products under Development by Top 10 Indications, H2 2017 Number of Products by Mechanism of Actions, H2 2017 Number of Products by Stage and Mechanism of Actions, H2 2017 Number of Products by Stage and Molecule Type, H2 2017
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